R&D Pilot Plant – Downstream

Location: Bengaluru, IN

We are seeking a skilled professional for a role focused on protein biochemistry and downstream processing.

Key Responsibilities:

• Preparation of reagents and buffers required for various purification steps.
• To ensure batch processed as per protocol for the PP driven activity & ensuring batch processed as per the requirement for non-PP driven activity
• Responsible for batch preparations, process execution and operational monitoring of various downstream purifications steps such as low-pressure chromatography, Nanofiltration, TFF etc.,
• Responsible for fumigation – Pre & post plating & incubation and eLN documentation
• Compliance with procedures related to quality systems. E.g. SOP, EOPs, IOPs, SAM, GM, etc.
• Adherence to safety, health and environment measures.
• Responsible for protein conc. check by Solo VPE / UV Spec and eLN result reporting and to maintain the inventory.
• To ensure GDP, eLN documentation & batch / data review.
• Responsible for sample segregation and transfer to respective teams.
• Should be able to work in shifts (A, B & C)

Technical/functional skills:

• Clear basic knowledge on protein biochemistry and downstream processing.
• Experience on handling purifications systems such as AKTA Pilot, AKTA Avant / Pure, TFF system etc.,
• Experience in handling analytical instruments like HPLC, Solo VPE, UV-Spectrophotometer etc.
• Ability to follow protocols and procedures for flawless execution of downstream batches.
• Handling of instrument calibration/maintenance, interacting with maintenance and vendor teams for effective instrument utilization and troubleshooting.
• Data compilation and Documentation skills with Ability to maintain raw data with clear traceability and in an orderly manner
• Capability of troubleshooting process and analytical challenges
• Should be well-versed in basic statistics and should have experience in using statistical software such as JMP, Minitab etc.
• Knowledge of LIMS-eLN

Educational/ Industry Experience Required:

• Minimum of BTech/M.Sc./ Master’s preferable in Biotechnology / Microbiology / Biochemistry with industry experience of 3-6 years
• Non PhD candidates are open to apply

Source ⇲
WhatJobs